Rangers captain James Tavernier believes the team are delivering on Steven Gerrard’s demands for the season so far and showed that by reaching the League Cup final.A 3-0 win over Hearts set the Ibrox side up for a showdown with Celtic next month for the first trophy of the season. It’s the first time the team have reached a final since 2016 and Tavernier has been part of teams that have fallen short in the last four over previous years. The right-back said that manager Gerrard had set challenges for his team and that so far, with the team competing on all fronts, players had stepped up to the mark.“It’s always difficult because you’re always playing with a new team since the previous year but we knew that this season we needed consistency and I think we’ve shown it throughout the season so far,” Tavernier said. “It’s just the level of performance that the boys have been putting in. “It’s what the gaffer demands and we’ve gone and delivered today.”A Filip Helander goal and a double from Alfredo Morelos saw Rangers see off Hearts without too much danger and Tavernier felt his side could be pleased with their efforts and look forward to the final.“That’s what we wanted to do before the game,” he said. “We haven’t had the greatest of (records in) semi-finals since I have been here but a club like Rangers needs to be in finals and competing for trophies.“We knew it would be a tough game today but we handled Hearts the best we could and came out on top.“Everybody wants to win a cup. “Us lads in that changing room all want to win a cup and be successful but we will concentrate on the Europa League and the (league) season and when the final comes along we will concentrate on that.”
Offspinner Gurkeerat Singh Mann registered his career best bowling figures as Punjab defeated a sorry-looking Andhra by seven wickets on the second day of a Group B Ranji Trophy cricket match on Saturday.After the fall of 17 wickets on the opening day, it was no different on Saturday as well as 16 more tumbled on a rank turner at the Dhruve Pandove stadium. Resuming their first innings at 127 for 7 in reply to Andhra 80 all out, Punjab added 20 more runs to finish on 147 to take a first innings lead of 67 runs.But the first innings lead hardly mattered as Punjab rode on Gurkeerat’s innings-best five for 38 to bundle out Andhra for a meagre 133 in their second innings, thereby setting a paltry target of 67 runs to chase for an outright win with more than two days play remaining in the match.Gurkeerat finished with career-best match figures of 9 for 52, which includes his first innings bowling figures of 4 for 14. Gurkeerat was ably supported by pacer Rajwinder Singh (3 for 33) who picked up three wickets in the second innings, while Sarabjit Ladda (2 for 40) accounted for two.The 67-run target was a mere formality for Punjab to complete which they achieved in 19.3 overs but not without losing three top-order batsmen. By virtue of this win, Punjab pocketed six points from the match while Andhra returned empty-handed.Brief Scores: Punjab: 147 & 67 for three in 19.3 overs (Mandeep Singh 22 not out; Hanumappa Shivraj 1/10). Andhra: 80 & 133 all out in 41.4 overs (KS Bharat 39; Gurkeerat Singh 5/38). Delhi reduced to 245 for 7 against OdishaSuryakant Pradhan’s four-wicket haul did the most damage as Delhi’s batting squandered a good start to be left tottering at 245 for 7 in their first innings on the second day of their Ranji Trophy Group A match against Odisha.advertisementOvernight 99 for 1, Delhi’s batsmen failed to convert their starts into big scores, allowing the home side to have the upper-hand. Middle-order batsman Milind Kumar top-scored for the visitors with a 138-ball 59, which was laced with eight fours. There were other decent contributions up the order as well but the absence of that one big sheet-anchor effort hurt Delhi.Brief scores: Delhi 1st innings: 245 for 7 in 115 overs (Milind Kumar 59, Dhruv Shorey 42, Gautam Gambhir 41, S Pradhan 4 for 83).UP take control against GujaratPraveen Kumar (5 for 16) and Saurabh Kumar (5 for 37) shared 10 wickets between them to bundle out Gajarat for 100 and give Uttar Pradesh 173-run first innings lead on the second day of their Ranji Trophy Group B match.At the close of play, UP were 163 for 7 in their second innings, with an overall lead of 336 runs and three wickets remaining. Earlier, resuming at 272 for 9 in their first innings, UP could add just one more run to their overnight score to finish at 273.In reply, Gujarat kept losing wickets at regular interval even as Praveen and Saurabh wrecked havoc. Only three home team batsmen could reach the double digit mark as they fell for a meagre 100 in 31.4 overs.Brief scores: Uttar Pradesh: 273 & 163 for 7 (Umang Sharma 66, Axar Patel 4/54). Gujarat: 100 all out (Parthiv Patel 39; Praveen Kumar 5/16, Saurabh Kumar 5/37).Bhatia scores ton as Rajasthan trail KarnatakaRajat Bhatia missed out on a century by just one run as Rajasthan reached 219 for 7, still trailing Karnataka’s first innings total by 62 runs, on the second day of a Group A Ranji Trophy match.At stumps, Deepak Chahar was batting on 13 and K Ajay Singh was on six. Earlier, resuming on 270 for 8 in their first essay, Karnataka could add just another 11 runs to their overnight total, getting all out for 281.Aniket Choudhary finished with best figures of 5 for 77 for Rajasthan. In reply, Rajasthan were struggling at 48 for 4 before Bhatia came to the team’s rescue.Brief scores: Karnataka 1st innings: 281 (Mayank Agarwal 66, Ravikumar Samarth 65; Aniket Choudhary 5/77). Rajasthan 1st innings: 219 for seven (Rajat Bhatia 99; R Vinay Kumar 2/39, David Mathias 2/41).
May 15 2018Malaria is still a deadly disease in tropical and subtropical regions. Every year the disease infects more than 200 million people worldwide, claiming several hundred thousand victims. Children are particularly vulnerable, with 90 percent of the victims under the age of five, according to the World Health Organization (WHO). Not only can malaria kill people, but it also impairs survivors’ quality of life and is a significant hindrance to economic development in the countries where it is prevalent.In many cases, however, the infected host carries the pathogen without presenting any external symptoms. “These are precisely the people we need to target in order to stop the disease spreading,” says Consuelo De Moraes, Professor of Biocommunication & Entomology at ETH Zurich.Recognizing changes in odorsBut how do you identify infected people with no external symptoms? Possibly by recognizing changes their odors – as demonstrated by the ETH professor and her colleagues in a paper just published in the journal Proceedings of the National Academy of Sciences. Working with collaborators at the International Centre for Insect Physiology and Ecology in Nairobi, these researchers examined volatile chemicals released from the skin of Kenyan children and identified characteristic patterns for both acute and asymptomatic malaria infections.In a previous study with mice, these researchers had demonstrated that changes in odors associated with malaria make infected individuals more attractive to mosquito vectors, which transmit the disease from one individual to another. “Based on our previous work we had reason to hope that similar changes in human odors might provide biomarkers that could be used for diagnosis,” De Moraes explains.To pursue their theory, the ETH scientists collected samples of volatile substances released from the skin of more than 400 Kenyan school children. This experiment involved placing a child’s foot or arm into sealed Teflon bag and passing an air current over the skin for about one hour. The air was then channeled through special filters that collected the volatile compounds. Using gas chromatography and mass spectrometry, the scientists then determined the identity and quantity of each compound to generate odor profiles for infected and healthy children.Important differencesFurther analysis of these profiles identified volatile biomarkers that enabled the researchers to clearly identify whether a child is infected with the malaria parasite. In addition, the odor profiles were found to be significantly different in the case of acute and asymptomatic infections. The researchers were able to detect the pathogen extremely reliably even when it was only present in minute quantities and was not yet observable under the microscope. Even for asymptomatic infections, the detection rate in the study was close to one hundred percent.Related StoriesGM fungus kills 99% of mosquitoes in Malaria-endemic region of AfricaSouthern Research team aims to discover new, safer antimalarial medicinesEngineers crack the code to quickly diagnose anti-malarial drug resistance”This high detection rate was encouraging,” says De Moraes, who was also surprised by the considerable differences found in the profiles of individuals with acute and asymptomatic malaria infections. “Initially we weren’t sure which chemical compounds we should be looking for,” explains the ETH professor. The body releases many different compounds from the skin that vary according to food intake, metabolism or illness. “The specific signature is not created by the presence or absence of specific compounds, but through a change in the concentrations of compounds that are also present in healthy people. Our task was to filter out the right signals from the extensive background noise.”The researchers hope that the biomarkers they have identified may be suitable for developing a relatively simple diagnostic tool that can be used in the field for the early detection of malaria. Methods such as Polymerase Chain Reaction (PCR), a DNA analysis technique, already exist for identifying malaria pathogens at an early stage. However, they are relatively expensive and require laboratory facilities, which makes their widespread use challenging, particularly in the poorer countries of the southern hemisphere.First step towards application”These new volatile biomarkers are an important first step. Now someone needs to develop an application that can be used cheaply and reliably in the field,” says Mark Mescher, an ETH Professor in the Institute of Integrative Biology who also worked on the project. The researchers hope to contribute to the development of such an application through continued partnership with the Bill and Melinda Gates Foundation, which provided some of the funding for this research.These ETH researchers also hope that similar methods might be effective in combatting other diseases. “We know that vector-borne pathogens often cause changes in the odors of infected individuals that influence vector behavior,” says Mescher, “which may create a chemical signature of infection that can be harnessed for diagnosis.” Source:https://www.ethz.ch/en/news-and-events/eth-news/news/2018/05/malaria-detectable-in-olfactory-cocktail.html